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The CD6/ALCAM pathway promotes lupus nephritis via T cell–mediated responses

The CD6/ALCAM pathway promotes lupus nephritis via T cell–mediated responses

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5da04dc9777b4f09af0bd8b936c10fd9

The CD6/ALCAM pathway promotes lupus nephritis via T cell–mediated responses

About this item

Full title

The CD6/ALCAM pathway promotes lupus nephritis via T cell–mediated responses

Publisher

United States: American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2022, Vol.132 (1), p.1-17

Language

English

Formats

Publication information

Publisher

United States: American Society for Clinical Investigation

More information

Scope and Contents

Contents

T cells are central to the pathogenesis of lupus nephritis (LN), a common complication of systemic lupus erythematosus (SLE). CD6 and its ligand, activated leukocyte cell adhesion molecule (ALCAM), are involved in T cell activation and trafficking. Previously, we showed that soluble ALCAM is increased in urine (uALCAM) of patients with LN, suggesti...

Alternative Titles

Full title

The CD6/ALCAM pathway promotes lupus nephritis via T cell–mediated responses

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_5da04dc9777b4f09af0bd8b936c10fd9

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5da04dc9777b4f09af0bd8b936c10fd9

Other Identifiers

ISSN

1558-8238,0021-9738

E-ISSN

1558-8238

DOI

10.1172/JCI147334

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