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HOXA9 has the hallmarks of a biological switch with implications in blood cancers

HOXA9 has the hallmarks of a biological switch with implications in blood cancers

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5dbdffc27b334b189ae56094325547a0

HOXA9 has the hallmarks of a biological switch with implications in blood cancers

About this item

Full title

HOXA9 has the hallmarks of a biological switch with implications in blood cancers

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2022-10, Vol.13 (1), p.5829-10, Article 5829

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Blood malignancies arise from the dysregulation of haematopoiesis. The type of blood cell and the specific order of oncogenic events initiating abnormal growth ultimately determine the cancer subtype and subsequent clinical outcome. HOXA9 plays an important role in acute myeloid leukaemia (AML) prognosis by promoting blood cell expansion and alteri...

Alternative Titles

Full title

HOXA9 has the hallmarks of a biological switch with implications in blood cancers

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_5dbdffc27b334b189ae56094325547a0

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5dbdffc27b334b189ae56094325547a0

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-022-33189-w

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