Restoration of p53 activity via intracellular protein delivery sensitizes triple negative breast can...
Restoration of p53 activity via intracellular protein delivery sensitizes triple negative breast cancer to anti-PD-1 immunotherapy
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London: BMJ Publishing Group Ltd
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Language
English
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London: BMJ Publishing Group Ltd
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BackgroundAlthough immune checkpoint inhibitors (ICIs) have been shown to yield promising therapeutic outcomes in a small subset of patients with triple negative breast cancer (TNBC), the majority of patients either do not respond or subsequently develop resistance. Recent studies have revealed the critical role of TP53 gene in cancer immunology. L...
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Restoration of p53 activity via intracellular protein delivery sensitizes triple negative breast cancer to anti-PD-1 immunotherapy
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TN_cdi_doaj_primary_oai_doaj_org_article_5dc74c03c0024904801f2397e4b72253
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5dc74c03c0024904801f2397e4b72253
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ISSN
2051-1426
E-ISSN
2051-1426
DOI
10.1136/jitc-2022-005068
