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Circulating mucosal-associated invariant T cells identify patients responding to anti-PD-1 therapy

Circulating mucosal-associated invariant T cells identify patients responding to anti-PD-1 therapy

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5dde8cd7955f4749b3113f29084ac913

Circulating mucosal-associated invariant T cells identify patients responding to anti-PD-1 therapy

About this item

Full title

Circulating mucosal-associated invariant T cells identify patients responding to anti-PD-1 therapy

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2021-03, Vol.12 (1), p.1669-11, Article 1669

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Immune checkpoint inhibitors are used for treating patients with metastatic melanoma. Since the response to treatment is variable, biomarkers are urgently needed to identify patients who may benefit from such therapy. Here, we combine single-cell RNA-sequencing and multiparameter flow cytometry to assess changes in circulating CD8
+
T cells i...

Alternative Titles

Full title

Circulating mucosal-associated invariant T cells identify patients responding to anti-PD-1 therapy

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_5dde8cd7955f4749b3113f29084ac913

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5dde8cd7955f4749b3113f29084ac913

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-021-21928-4

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