Coupling of ribosome biogenesis and translation initiation in human mitochondria
Coupling of ribosome biogenesis and translation initiation in human mitochondria
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Biogenesis of mitoribosomes requires dedicated chaperones, RNA-modifying enzymes, and GTPases, and defects in mitoribosome assembly lead to severe mitochondriopathies in humans. Here, we characterize late-step assembly states of the small mitoribosomal subunit (mtSSU) by combining genetic perturbation and mutagenesis analysis with biochemical and s...
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Full title
Coupling of ribosome biogenesis and translation initiation in human mitochondria
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TN_cdi_doaj_primary_oai_doaj_org_article_5ddfc481cd164091ba9d7325f128c881
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5ddfc481cd164091ba9d7325f128c881
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-025-58827-x
