Genetic architecture of epigenetic and neuronal ageing rates in human brain regions
Genetic architecture of epigenetic and neuronal ageing rates in human brain regions
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Publisher
London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Identifying genes regulating the pace of epigenetic ageing represents a new frontier in genome-wide association studies (GWASs). Here using 1,796 brain samples from 1,163 individuals, we carry out a GWAS of two DNA methylation-based biomarkers of brain age: the epigenetic ageing rate and estimated proportion of neurons. Locus 17q11.2 is significant...
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Genetic architecture of epigenetic and neuronal ageing rates in human brain regions
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TN_cdi_doaj_primary_oai_doaj_org_article_5e03eee242f245478c247604d60390ed
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5e03eee242f245478c247604d60390ed
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms15353
