Dietary fatty acids promote lipid droplet diversity through seipin enrichment in an ER subdomain
Dietary fatty acids promote lipid droplet diversity through seipin enrichment in an ER subdomain
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Author / Creator
Cao, Zhe , Hao, Yan , Fung, Chun Wing , Lee, Yiu Yiu , Wang, Pengfei , Li, Xuesong , Xie, Kang , Lam, Wen Jiun , Qiu, Yifei , Tang, Ben Zhong , Shui, Guanghou , Liu, Pingsheng , Qu, Jianan , Kang, Byung-Ho and Mak, Ho Yi
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Contents
Exogenous metabolites from microbial and dietary origins have profound effects on host metabolism. Here, we report that a sub-population of lipid droplets (LDs), which are conserved organelles for fat storage, is defined by metabolite-modulated targeting of the
C. elegans
seipin ortholog, SEIP-1. Loss of SEIP-1 function reduces the size of a...
Alternative Titles
Full title
Dietary fatty acids promote lipid droplet diversity through seipin enrichment in an ER subdomain
Authors, Artists and Contributors
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_5e0412232df841dd8f66c2377abdde09
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5e0412232df841dd8f66c2377abdde09
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-10835-4
