Enhanced expression of membrane proteins in E. coli with a PBAD promoter mutant: synergies with chap...
Enhanced expression of membrane proteins in E. coli with a PBAD promoter mutant: synergies with chaperone pathway engineering strategies
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BioMed Central Ltd
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English
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BioMed Central Ltd
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BACKGROUND: Membrane proteins (MPs) populate 20-30% of genomes sequenced to date and hold potential as therapeutic targets as well as for practical applications in bionanotechnology. However, MP toxicity and low yields in normally robust expression hosts such as E. coli has curtailed progress in our understanding of their structure and function. RE...
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Enhanced expression of membrane proteins in E. coli with a PBAD promoter mutant: synergies with chaperone pathway engineering strategies
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TN_cdi_doaj_primary_oai_doaj_org_article_5e04c514bada4ce8a19a7a18abbdd98a
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5e04c514bada4ce8a19a7a18abbdd98a
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ISSN
1475-2859
E-ISSN
1475-2859
DOI
10.1186/1475-2859-10-105
