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Comprehensive SNP array study of frequently used neuroblastoma cell lines; copy neutral loss of hete...

Comprehensive SNP array study of frequently used neuroblastoma cell lines; copy neutral loss of hete...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5e37812c6e954665a11cd0a4565e3bb6

Comprehensive SNP array study of frequently used neuroblastoma cell lines; copy neutral loss of heterozygosity is common in the cell lines but uncommon in primary tumors

About this item

Full title

Comprehensive SNP array study of frequently used neuroblastoma cell lines; copy neutral loss of heterozygosity is common in the cell lines but uncommon in primary tumors

Publisher

England: BioMed Central Ltd

Journal title

BMC genomics, 2011-09, Vol.12 (1), p.443-443, Article 443

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Copy neutral loss of heterozygosity (CN-LOH) refers to a special case of LOH occurring without any resulting loss in copy number. These alterations is sometimes seen in tumors as a way to inactivate a tumor suppressor gene and have been found to be important in several types of cancer.
We have used high density single nucleotide polymorphism arr...

Alternative Titles

Full title

Comprehensive SNP array study of frequently used neuroblastoma cell lines; copy neutral loss of heterozygosity is common in the cell lines but uncommon in primary tumors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_5e37812c6e954665a11cd0a4565e3bb6

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5e37812c6e954665a11cd0a4565e3bb6

Other Identifiers

ISSN

1471-2164

E-ISSN

1471-2164

DOI

10.1186/1471-2164-12-443