Targeting necroptosis in muscle fibers ameliorates inflammatory myopathies
Targeting necroptosis in muscle fibers ameliorates inflammatory myopathies
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Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Muscle cell death in polymyositis is induced by CD8
+
cytotoxic T lymphocytes. We hypothesized that the injured muscle fibers release pro-inflammatory molecules, which would further accelerate CD8
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cytotoxic T lymphocytes-induced muscle injury, and inhibition of the cell death of muscle fibers could be a novel therapeutic strategy to s...
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Full title
Targeting necroptosis in muscle fibers ameliorates inflammatory myopathies
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TN_cdi_doaj_primary_oai_doaj_org_article_5e5ae3df2a554b49bed6089fd7ec2204
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5e5ae3df2a554b49bed6089fd7ec2204
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-27875-4
