Role of PDLIM1 in hepatic stellate cell activation and liver fibrosis progression
Role of PDLIM1 in hepatic stellate cell activation and liver fibrosis progression
About this item
Full title
Author / Creator
Ye, Bingyu , Yu, Mengli , Yue, Meijuan , Yin, Man , Zhang, Chunyan , Wang, Qiwen , Ding, Xinru , Shen, Wenlong and Zhao, Zhihu
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Liver fibrosis is caused by chronic hepatic injury and may lead to cirrhosis, and even hepatocellular carcinoma. When hepatic stellate cells (HSCs) are activated by liver injury, they transdifferentiate into myofibroblasts, which secrete extracellular matrix proteins that generate the fibrous scar. Therefore, it is extremely urgent to find safe and...
Alternative Titles
Full title
Role of PDLIM1 in hepatic stellate cell activation and liver fibrosis progression
Authors, Artists and Contributors
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_5e770de7892e42e6a0d86b13ecce6525
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5e770de7892e42e6a0d86b13ecce6525
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-023-38144-3
