Reno-Protective Effect of GLP-1 Receptor Agonists in Type1 Diabetes: Dual Action on TRPC6 and NADPH...
Reno-Protective Effect of GLP-1 Receptor Agonists in Type1 Diabetes: Dual Action on TRPC6 and NADPH Oxidases
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Basel: MDPI AG
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Language
English
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Basel: MDPI AG
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Contents
Diabetic kidney disease (DKD), a serious diabetic complication, results in podocyte loss and proteinuria through NADPH oxidases (NOX)-mediated ROS production. DUOX1 and 2 are NOX enzymes that require calcium for their activation which enters renal cells through the pivotal TRPC channels. Hypoglycemic drugs such as liraglutide can interfere with thi...
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Full title
Reno-Protective Effect of GLP-1 Receptor Agonists in Type1 Diabetes: Dual Action on TRPC6 and NADPH Oxidases
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TN_cdi_doaj_primary_oai_doaj_org_article_5ebf40b530ec45c1a9a2087a15739f2b
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5ebf40b530ec45c1a9a2087a15739f2b
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ISSN
2227-9059
E-ISSN
2227-9059
DOI
10.3390/biomedicines9101360
