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Degeneration of muscle spindles in a murine model of Pompe disease

Degeneration of muscle spindles in a murine model of Pompe disease

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5ec2dcb3abbd4c4a8f73f87c27814f52

Degeneration of muscle spindles in a murine model of Pompe disease

About this item

Full title

Degeneration of muscle spindles in a murine model of Pompe disease

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2023-04, Vol.13 (1), p.6555-16, Article 6555

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Pompe disease is a debilitating medical condition caused by a functional deficiency of lysosomal acid alpha-glucosidase (GAA). In addition to muscle weakness, people living with Pompe disease experience motor coordination deficits including an instable gait and posture. We reasoned that an impaired muscle spindle function might contribute to these...

Alternative Titles

Full title

Degeneration of muscle spindles in a murine model of Pompe disease

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_5ec2dcb3abbd4c4a8f73f87c27814f52

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5ec2dcb3abbd4c4a8f73f87c27814f52

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-023-33543-y

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