AHA1 upregulates IDH1 and metabolic activity to promote growth and metastasis and predicts prognosis...
AHA1 upregulates IDH1 and metabolic activity to promote growth and metastasis and predicts prognosis in osteosarcoma
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Author / Creator
Zheng, Diwei , Liu, Weihai , Xie, Wenlin , Huang, Guanyu , Jiang, Qiwei , Yang, Yang , Huang, Jiarong , Xing, Zihao , Yuan, Mengling , Wei, Mengning , Li, Yao , Yin, Junqiang , Shen, Jingnan and Shi, Zhi
Publisher
London: Nature Publishing Group UK
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Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Osteosarcoma (OS) is the most common primary malignant bone tumor in children and adolescents. Although activator of HSP90 ATPase activity 1 (AHA1) is reported to be a potential oncogene, its role in osteosarcoma progression remains largely unclear. Since metabolism reprogramming is involved in tumorigenesis and cancer metastasis, the relationship...
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Full title
AHA1 upregulates IDH1 and metabolic activity to promote growth and metastasis and predicts prognosis in osteosarcoma
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_5ed2f433cbfe4e318fc1e650137569fa
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5ed2f433cbfe4e318fc1e650137569fa
Other Identifiers
ISSN
2059-3635,2095-9907
E-ISSN
2059-3635
DOI
10.1038/s41392-020-00387-1
