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Papillary thyroid carcinoma tall cell variant shares accumulation of mitochondria, mitochondrial DNA...

Papillary thyroid carcinoma tall cell variant shares accumulation of mitochondria, mitochondrial DNA...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5eea82949f244e12ae91cb2be6de33bb

Papillary thyroid carcinoma tall cell variant shares accumulation of mitochondria, mitochondrial DNA mutations, and loss of oxidative phosphorylation complex I integrity with oncocytic tumors

About this item

Full title

Papillary thyroid carcinoma tall cell variant shares accumulation of mitochondria, mitochondrial DNA mutations, and loss of oxidative phosphorylation complex I integrity with oncocytic tumors

Publisher

Hoboken, USA: John Wiley & Sons, Inc

Journal title

The Journal of Pathology: Clinical Research, 2022-03, Vol.8 (2), p.155-168

Language

English

Formats

Publication information

Publisher

Hoboken, USA: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

Papillary thyroid carcinoma tall cell variant (PTC‐TCV), a form of PTC regarded as an aggressive subtype, shares several morphologic features with oncocytic tumors. Pathogenic homoplasmic/highly heteroplasmic somatic mitochondrial DNA (mtDNA) mutations, usually affecting oxidative phosphorylation (OXPHOS) complex I subunits, are hallmarks of oncocy...

Alternative Titles

Full title

Papillary thyroid carcinoma tall cell variant shares accumulation of mitochondria, mitochondrial DNA mutations, and loss of oxidative phosphorylation complex I integrity with oncocytic tumors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_5eea82949f244e12ae91cb2be6de33bb

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5eea82949f244e12ae91cb2be6de33bb

Other Identifiers

ISSN

2056-4538

E-ISSN

2056-4538

DOI

10.1002/cjp2.247

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