Application of Prostate Cancer Models for Preclinical Study: Advantages and Limitations of Cell Line...
Application of Prostate Cancer Models for Preclinical Study: Advantages and Limitations of Cell Lines, Patient-Derived Xenografts, and Three-Dimensional Culture of Patient-Derived Cells
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Switzerland: MDPI AG
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English
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Switzerland: MDPI AG
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Various preclinical models have been developed to clarify the pathophysiology of prostate cancer (PCa). Traditional PCa cell lines from clinical metastatic lesions, as exemplified by DU-145, PC-3, and LNCaP cells, are useful tools to define mechanisms underlying tumorigenesis and drug resistance. Cell line-based experiments, however, have limitatio...
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Application of Prostate Cancer Models for Preclinical Study: Advantages and Limitations of Cell Lines, Patient-Derived Xenografts, and Three-Dimensional Culture of Patient-Derived Cells
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TN_cdi_doaj_primary_oai_doaj_org_article_5f15e7494c974e8e8551c5b8a4a3ea5b
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5f15e7494c974e8e8551c5b8a4a3ea5b
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ISSN
2073-4409
E-ISSN
2073-4409
DOI
10.3390/cells8010074
