GEP analysis validates high risk MDS and acute myeloid leukemia post MDS mice models and highlights...
GEP analysis validates high risk MDS and acute myeloid leukemia post MDS mice models and highlights novel dysregulated pathways
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Author / Creator
Guerenne, Laura , Beurlet, Stéphanie , Said, Mohamed , Gorombei, Petra , Le Pogam, Carole , Guidez, Fabien , de la Grange, Pierre , Omidvar, Nader , Vanneaux, Valérie , Mills, Ken , Mufti, Ghulam J , Sarda-Mantel, Laure , Noguera, Maria Elena , Pla, Marika , Fenaux, Pierre , Padua, Rose Ann , Chomienne, Christine and Krief, Patricia
Publisher
England: BioMed Central Ltd
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English
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Publisher
England: BioMed Central Ltd
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Contents
In spite of the recent discovery of genetic mutations in most myelodysplasic (MDS) patients, the pathophysiology of these disorders still remains poorly understood, and only few in vivo models are available to help unravel the disease.
We performed global specific gene expression profiling and functional pathway analysis in purified Sca1+ cells...
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GEP analysis validates high risk MDS and acute myeloid leukemia post MDS mice models and highlights novel dysregulated pathways
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TN_cdi_doaj_primary_oai_doaj_org_article_5f34a28afe924b7bb0e3dc96b14f7206
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5f34a28afe924b7bb0e3dc96b14f7206
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ISSN
1756-8722
E-ISSN
1756-8722
DOI
10.1186/s13045-016-0235-8
