Chiral gold nanoparticles enantioselectively rescue memory deficits in a mouse model of Alzheimer’s...
Chiral gold nanoparticles enantioselectively rescue memory deficits in a mouse model of Alzheimer’s disease
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Author / Creator
Hou, Ke , Zhao, Jing , Wang, Hui , Li, Bin , Li, Kexin , Shi, Xinghua , Wan, Kaiwei , Ai, Jing , Lv, Jiawei , Wang, Dawei , Huang, Qunxing , Wang, Huayi , Cao, Qin , Liu, Shaoqin and Tang, Zhiyong
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Preventing aggregation of amyloid beta (Aβ) peptides is a promising strategy for the treatment of Alzheimer’s disease (AD), and gold nanoparticles have previously been explored as a potential anti-Aβ therapeutics. Here we design and prepare 3.3 nm L- and D-glutathione stabilized gold nanoparticles (denoted as L3.3 and D3.3, respectively). Both chir...
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Full title
Chiral gold nanoparticles enantioselectively rescue memory deficits in a mouse model of Alzheimer’s disease
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TN_cdi_doaj_primary_oai_doaj_org_article_5f3b317f18a94dfbb108df54eea815d3
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5f3b317f18a94dfbb108df54eea815d3
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-18525-2
