The anti-malarial atovaquone increases radiosensitivity by alleviating tumour hypoxia
The anti-malarial atovaquone increases radiosensitivity by alleviating tumour hypoxia
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Tumour hypoxia renders cancer cells resistant to cancer therapy, resulting in markedly worse clinical outcomes. To find clinical candidate compounds that reduce hypoxia in tumours, we conduct a high-throughput screen for oxygen consumption rate (OCR) reduction and identify a number of drugs with this property. For this study we focus on the anti-ma...
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The anti-malarial atovaquone increases radiosensitivity by alleviating tumour hypoxia
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TN_cdi_doaj_primary_oai_doaj_org_article_5fcde319119841a9a1a9daedc3b99552
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5fcde319119841a9a1a9daedc3b99552
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms12308
