Differential TAM receptor–ligand–phospholipid interactions delimit differential TAM bioactivities
Differential TAM receptor–ligand–phospholipid interactions delimit differential TAM bioactivities
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England: eLife Sciences Publications Ltd
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Language
English
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England: eLife Sciences Publications Ltd
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The TAM receptor tyrosine kinases Tyro3, Axl, and Mer regulate key features of cellular physiology, yet the differential activities of the TAM ligands Gas6 and Protein S are poorly understood. We have used biochemical and genetic analyses to delineate the rules for TAM receptor–ligand engagement and find that the TAMs segregate into two groups base...
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Full title
Differential TAM receptor–ligand–phospholipid interactions delimit differential TAM bioactivities
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TN_cdi_doaj_primary_oai_doaj_org_article_5fea7649da76453ba6611429febbdc74
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5fea7649da76453ba6611429febbdc74
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.03385
