CD4 and CD8 co-receptors modulate functional avidity of CD1b-restricted T cells
CD4 and CD8 co-receptors modulate functional avidity of CD1b-restricted T cells
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London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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T cells recognize mycobacterial glycolipid (mycolipid) antigens presented by CD1b molecules, but the role of CD4 and CD8 co-receptors in mycolipid recognition is unknown. Here we show CD1b-mycolipid tetramers reveal a hierarchy in which circulating T cells expressing CD4 or CD8 co-receptor stain with a higher tetramer mean fluorescence intensity th...
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Full title
CD4 and CD8 co-receptors modulate functional avidity of CD1b-restricted T cells
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TN_cdi_doaj_primary_oai_doaj_org_article_5ffbba8ac40b4631bfdd4ca36548cb97
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_5ffbba8ac40b4631bfdd4ca36548cb97
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-27764-w
