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Preparation of a First 18F-Labeled Agonist for M1 Muscarinic Acetylcholine Receptors

Preparation of a First 18F-Labeled Agonist for M1 Muscarinic Acetylcholine Receptors

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_601a7baf02da4c3c892d1c769490d6fc

Preparation of a First 18F-Labeled Agonist for M1 Muscarinic Acetylcholine Receptors

About this item

Full title

Preparation of a First 18F-Labeled Agonist for M1 Muscarinic Acetylcholine Receptors

Publisher

Basel: MDPI AG

Journal title

Molecules (Basel, Switzerland), 2020-06, Vol.25 (12), p.2880

Language

English

Formats

Publication information

Publisher

Basel: MDPI AG

More information

Scope and Contents

Contents

M1 muscarinic acetylcholine receptors (mAChRs) are abundant in postsynaptic nerve terminals of all forebrain regions and have been implicated in the cognitive decline associated with Alzheimer’s disease and other CNS pathologies. Consequently, major efforts have been spent in the development of subtype-selective positron emission tomography (PET) t...

Alternative Titles

Full title

Preparation of a First 18F-Labeled Agonist for M1 Muscarinic Acetylcholine Receptors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_601a7baf02da4c3c892d1c769490d6fc

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_601a7baf02da4c3c892d1c769490d6fc

Other Identifiers

ISSN

1420-3049

E-ISSN

1420-3049

DOI

10.3390/molecules25122880

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