The structural basis of lipid scrambling and inactivation in the endoplasmic reticulum scramblase TM...
The structural basis of lipid scrambling and inactivation in the endoplasmic reticulum scramblase TMEM16K
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Author / Creator
Bushell, Simon R. , Pike, Ashley C. W. , Falzone, Maria E. , Rorsman, Nils J. G. , Ta, Chau M. , Corey, Robin A. , Newport, Thomas D. , Christianson, John C. , Scofano, Lara F. , Shintre, Chitra A. , Tessitore, Annamaria , Chu, Amy , Wang, Qinrui , Shrestha, Leela , Mukhopadhyay, Shubhashish M. M. , Love, James D. , Burgess-Brown, Nicola A. , Sitsapesan, Rebecca , Stansfeld, Phillip J. , Huiskonen, Juha T. , Tammaro, Paolo , Accardi, Alessio and Carpenter, Elisabeth P.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Membranes in cells have defined distributions of lipids in each leaflet, controlled by lipid scramblases and flip/floppases. However, for some intracellular membranes such as the endoplasmic reticulum (ER) the scramblases have not been identified. Members of the TMEM16 family have either lipid scramblase or chloride channel activity. Although TMEM1...
Alternative Titles
Full title
The structural basis of lipid scrambling and inactivation in the endoplasmic reticulum scramblase TMEM16K
Authors, Artists and Contributors
Author / Creator
Pike, Ashley C. W.
Falzone, Maria E.
Rorsman, Nils J. G.
Ta, Chau M.
Corey, Robin A.
Newport, Thomas D.
Christianson, John C.
Scofano, Lara F.
Shintre, Chitra A.
Tessitore, Annamaria
Chu, Amy
Wang, Qinrui
Shrestha, Leela
Mukhopadhyay, Shubhashish M. M.
Love, James D.
Burgess-Brown, Nicola A.
Sitsapesan, Rebecca
Stansfeld, Phillip J.
Huiskonen, Juha T.
Tammaro, Paolo
Accardi, Alessio
Carpenter, Elisabeth P.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_602dd2cc133c49529d8807b7b0d875ca
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_602dd2cc133c49529d8807b7b0d875ca
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-11753-1
