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The potassium channel Kv1.3 as a therapeutic target for immunocytoprotection after reperfusion

The potassium channel Kv1.3 as a therapeutic target for immunocytoprotection after reperfusion

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6050be43b9a14b89a41f250f8452b22e

The potassium channel Kv1.3 as a therapeutic target for immunocytoprotection after reperfusion

About this item

Full title

The potassium channel Kv1.3 as a therapeutic target for immunocytoprotection after reperfusion

Publisher

United States: John Wiley & Sons, Inc

Journal title

Annals of clinical and translational neurology, 2021-10, Vol.8 (10), p.2070-2082

Language

English

Formats

Publication information

Publisher

United States: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

Objective
The voltage‐gated potassium channel Kv1.3, which is expressed on activated, disease‐associated microglia and memory T cells, constitutes an attractive target for immunocytoprotection after endovascular thrombectomy (EVT). Using young male mice and rats we previously demonstrated that the Kv1.3 blocker PAP‐1 when started 12 h after repe...

Alternative Titles

Full title

The potassium channel Kv1.3 as a therapeutic target for immunocytoprotection after reperfusion

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_6050be43b9a14b89a41f250f8452b22e

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6050be43b9a14b89a41f250f8452b22e

Other Identifiers

ISSN

2328-9503

E-ISSN

2328-9503

DOI

10.1002/acn3.51456

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