Phase separation and zinc-induced transition modulate synaptic distribution and association of autis...
Phase separation and zinc-induced transition modulate synaptic distribution and association of autism-linked CTTNBP2 and SHANK3
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Many synaptic proteins form biological condensates via liquid-liquid phase separation (LLPS). Synaptopathy, a key feature of autism spectrum disorders (ASD), is likely relevant to the impaired phase separation and/or transition of ASD-linked synaptic proteins. Here, we report that LLPS and zinc-induced liquid-to-gel phase transition regulate the sy...
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Phase separation and zinc-induced transition modulate synaptic distribution and association of autism-linked CTTNBP2 and SHANK3
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TN_cdi_doaj_primary_oai_doaj_org_article_606759d0679e4b38a5a84d6adda6e45a
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_606759d0679e4b38a5a84d6adda6e45a
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-022-30353-0
