The induction of peripheral trained immunity in the pancreas incites anti-tumor activity to control...
The induction of peripheral trained immunity in the pancreas incites anti-tumor activity to control pancreatic cancer progression
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Author / Creator
Geller, Anne E. , Shrestha, Rejeena , Woeste, Matthew R. , Guo, Haixun , Hu, Xiaoling , Ding, Chuanlin , Andreeva, Kalina , Chariker, Julia H. , Zhou, Mingqian , Tieri, David , Watson, Corey T. , Mitchell, Robert A. , Zhang, Huang-ge , Li, Yan , Martin II, Robert C. G. , Rouchka, Eric C. and Yan, Jun
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Despite the remarkable success of immunotherapy in many types of cancer, pancreatic ductal adenocarcinoma has yet to benefit. Innate immune cells are critical to anti-tumor immunosurveillance and recent studies have revealed that these populations possess a form of memory, termed trained innate immunity, which occurs through transcriptomic, epigene...
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Full title
The induction of peripheral trained immunity in the pancreas incites anti-tumor activity to control pancreatic cancer progression
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TN_cdi_doaj_primary_oai_doaj_org_article_60896ee968874b53b16e34db9dd843ba
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_60896ee968874b53b16e34db9dd843ba
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-022-28407-4