Disrupting tumour vasculature and recruitment of aPDL1-loaded platelets control tumour metastasis
Disrupting tumour vasculature and recruitment of aPDL1-loaded platelets control tumour metastasis
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Author / Creator
Li, Hongjun , Wang, Zejun , Chen, Zhaowei , Ci, Tianyuan , Chen, Guojun , Wen, Di , Li, Ruoxin , Wang, Jinqiang , Meng, Huan , Bryan Bell, R. , Gu, Zhifeng , Dotti, Gianpietro and Gu, Zhen
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Although therapies of cancer are advancing, it remains challenging for therapeutics to reach the sites of metastasis, which accounts for majority of cancer associated death. In this study, we have developed a strategy that guides an anti-programmed cell death-ligand 1 (aPDL1) antibody to accumulate in metastatic lesions to promote anti-tumour immun...
Alternative Titles
Full title
Disrupting tumour vasculature and recruitment of aPDL1-loaded platelets control tumour metastasis
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TN_cdi_doaj_primary_oai_doaj_org_article_608a4349715044a79d78a3f8c89aa2c6
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_608a4349715044a79d78a3f8c89aa2c6
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-22674-3
