The immune checkpoint B7x expands tumor-infiltrating Tregs and promotes resistance to anti-CTLA-4 th...
The immune checkpoint B7x expands tumor-infiltrating Tregs and promotes resistance to anti-CTLA-4 therapy
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Immune checkpoint molecules play critical roles in regulating the anti-tumor immune response, and tumor cells often exploit these pathways to inhibit and evade the immune system. The B7-family immune checkpoint B7x is widely expressed in a broad variety of cancer types, and is generally associated with advanced disease progression and poorer clinic...
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The immune checkpoint B7x expands tumor-infiltrating Tregs and promotes resistance to anti-CTLA-4 therapy
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TN_cdi_doaj_primary_oai_doaj_org_article_60920b90f3ff4389949136f7a8e26dd2
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_60920b90f3ff4389949136f7a8e26dd2
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-022-30143-8
