The mitochondrial Ca2+ uniporter channel synergizes with fluid shear stress to induce mitochondrial...
The mitochondrial Ca2+ uniporter channel synergizes with fluid shear stress to induce mitochondrial Ca2+ oscillations
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
The mitochondrial calcium (Ca
2+
) uniporter (MCU) channel is responsible for mitochondrial Ca
2+
influx. Its expression was found to be upregulated in endothelial cells (ECs) under cardiovascular disease conditions. Since the role of MCU in regulating cytosolic Ca
2+
homeostasis in ECs exposed to shear stress (SS) is unknown, we...
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Full title
The mitochondrial Ca2+ uniporter channel synergizes with fluid shear stress to induce mitochondrial Ca2+ oscillations
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TN_cdi_doaj_primary_oai_doaj_org_article_60992396b0f048ee90a689948b2e1637
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_60992396b0f048ee90a689948b2e1637
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-022-25583-7
