Spatially resolved proteomic profiling identifies tumor cell CD44 as a biomarker associated with sen...
Spatially resolved proteomic profiling identifies tumor cell CD44 as a biomarker associated with sensitivity to PD-1 axis blockade in advanced non-small-cell lung cancer
About this item
Full title
Author / Creator
Moutafi, Myrto K , Molero, Magdalena , Martinez Morilla, Sandra , Baena, Javier , Vathiotis, Ioannis A , Gavrielatou, Niki , Castro-Labrador, Laura , de Garibay, Gorka Ruiz , Adradas, Vera , Orive, Daniel , Valencia, Karmele , Calvo, Alfonso , Montuenga, Luis M , Ponce Aix, S , Schalper, Kurt A , Herbst, Roy S , Paz-Ares, Luis , Rimm, David L and Zugazagoitia, Jon
Publisher
England: BMJ Publishing Group Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: BMJ Publishing Group Ltd
Subjects
More information
Scope and Contents
Contents
BackgroundMost patients with advanced non-small-cell lung cancer (NSCLC) fail to derive significant benefit from programmed cell death protein-1 (PD-1) axis blockade, and new biomarkers of response are needed. In this study, we aimed to discover and validate spatially resolved protein markers associated with sensitivity to PD-1 axis inhibition in N...
Alternative Titles
Full title
Spatially resolved proteomic profiling identifies tumor cell CD44 as a biomarker associated with sensitivity to PD-1 axis blockade in advanced non-small-cell lung cancer
Authors, Artists and Contributors
Author / Creator
Molero, Magdalena
Martinez Morilla, Sandra
Baena, Javier
Vathiotis, Ioannis A
Gavrielatou, Niki
Castro-Labrador, Laura
de Garibay, Gorka Ruiz
Adradas, Vera
Orive, Daniel
Valencia, Karmele
Calvo, Alfonso
Montuenga, Luis M
Ponce Aix, S
Schalper, Kurt A
Herbst, Roy S
Paz-Ares, Luis
Rimm, David L
Zugazagoitia, Jon
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_60a055bbf4cc41e595b426409dc06526
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_60a055bbf4cc41e595b426409dc06526
Other Identifiers
ISSN
2051-1426
E-ISSN
2051-1426
DOI
10.1136/jitc-2022-004757
