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Real-time monitoring of peptidoglycan synthesis by membrane-reconstituted penicillin-binding protein...

Real-time monitoring of peptidoglycan synthesis by membrane-reconstituted penicillin-binding protein...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_60ad42399ae443119b81485e716b10c5

Real-time monitoring of peptidoglycan synthesis by membrane-reconstituted penicillin-binding proteins

About this item

Full title

Real-time monitoring of peptidoglycan synthesis by membrane-reconstituted penicillin-binding proteins

Publisher

England: eLife Science Publications, Ltd

Journal title

eLife, 2021-02, Vol.10

Language

English

Formats

Publication information

Publisher

England: eLife Science Publications, Ltd

More information

Scope and Contents

Contents

Peptidoglycan is an essential component of the bacterial cell envelope that surrounds the cytoplasmic membrane to protect the cell from osmotic lysis. Important antibiotics such as β-lactams and glycopeptides target peptidoglycan biosynthesis. Class A penicillin-binding proteins (PBPs) are bifunctional membrane-bound peptidoglycan synthases that po...

Alternative Titles

Full title

Real-time monitoring of peptidoglycan synthesis by membrane-reconstituted penicillin-binding proteins

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_60ad42399ae443119b81485e716b10c5

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_60ad42399ae443119b81485e716b10c5

Other Identifiers

ISSN

2050-084X

E-ISSN

2050-084X

DOI

10.7554/eLife.61525

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