Experimental priming of encephalitogenic Th1/Th17 cells requires pertussis toxin-driven IL-1β produc...
Experimental priming of encephalitogenic Th1/Th17 cells requires pertussis toxin-driven IL-1β production by myeloid cells
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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CD4
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Th17 are heterogeneous in terms of cytokine production and capacity to initiate autoimmune diseases, such as experimental autoimmune encephalomyelitis (EAE). Here we demonstrate that experimental priming of encephalitogenic Th cells expressing RORγt and T-bet and producing IL-17A, IFN-γ and GM-CSF but not IL-10 (Th1/Th17), is dependent...
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Experimental priming of encephalitogenic Th1/Th17 cells requires pertussis toxin-driven IL-1β production by myeloid cells
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TN_cdi_doaj_primary_oai_doaj_org_article_60aea11e72f949ae8b88198b96e820eb
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_60aea11e72f949ae8b88198b96e820eb
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms11541
