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Plasma membrane overgrowth causes fibrotic collagen accumulation and immune activation in Drosophila...

Plasma membrane overgrowth causes fibrotic collagen accumulation and immune activation in Drosophila...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_60e00f85c8c94b53a33663ba5e46eecb

Plasma membrane overgrowth causes fibrotic collagen accumulation and immune activation in Drosophila adipocytes

About this item

Full title

Plasma membrane overgrowth causes fibrotic collagen accumulation and immune activation in Drosophila adipocytes

Publisher

England: eLife Sciences Publications Ltd

Journal title

eLife, 2015-06, Vol.4, p.e07187-e07187

Language

English

Formats

Publication information

Publisher

England: eLife Sciences Publications Ltd

More information

Scope and Contents

Contents

Many chronic diseases are associated with fibrotic deposition of Collagen and other matrix proteins. Little is known about the factors that determine preferential onset of fibrosis in particular tissues. Here we show that plasma membrane (PM) overgrowth causes pericellular Collagen accumulation in Drosophila adipocytes. We found that loss of Dynami...

Alternative Titles

Full title

Plasma membrane overgrowth causes fibrotic collagen accumulation and immune activation in Drosophila adipocytes

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_60e00f85c8c94b53a33663ba5e46eecb

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_60e00f85c8c94b53a33663ba5e46eecb

Other Identifiers

ISSN

2050-084X

E-ISSN

2050-084X

DOI

10.7554/eLife.07187

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