Mitochondrial mutations drive prostate cancer aggression
Mitochondrial mutations drive prostate cancer aggression
About this item
Full title
Author / Creator
Hopkins, Julia F. , Sabelnykova, Veronica Y. , Weischenfeldt, Joachim , Simon, Ronald , Aguiar, Jennifer A. , Alkallas, Rached , Heisler, Lawrence E. , Zhang, Junyan , Watson, John D. , Chua, Melvin L. K. , Fraser, Michael , Favero, Francesco , Lawerenz, Chris , Plass, Christoph , Sauter, Guido , McPherson, John D. , van der Kwast, Theodorus , Korbel, Jan , Schlomm, Thorsten , Bristow, Robert G. and Boutros, Paul C.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Nuclear mutations are well known to drive tumor incidence, aggression and response to therapy. By contrast, the frequency and roles of mutations in the maternally inherited mitochondrial genome are poorly understood. Here we sequence the mitochondrial genomes of 384 localized prostate cancer patients, and identify a median of one mitochondrial sing...
Alternative Titles
Full title
Mitochondrial mutations drive prostate cancer aggression
Authors, Artists and Contributors
Author / Creator
Sabelnykova, Veronica Y.
Weischenfeldt, Joachim
Simon, Ronald
Aguiar, Jennifer A.
Alkallas, Rached
Heisler, Lawrence E.
Zhang, Junyan
Watson, John D.
Chua, Melvin L. K.
Fraser, Michael
Favero, Francesco
Lawerenz, Chris
Plass, Christoph
Sauter, Guido
McPherson, John D.
van der Kwast, Theodorus
Korbel, Jan
Schlomm, Thorsten
Bristow, Robert G.
Boutros, Paul C.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_60e16080a49e4b41a40aef4ed8595ea3
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_60e16080a49e4b41a40aef4ed8595ea3
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-017-00377-y
