Inhibition of Rho-Kinase Downregulates Th17 Cells and Ameliorates Hepatic Fibrosis by Schistosoma ja...
Inhibition of Rho-Kinase Downregulates Th17 Cells and Ameliorates Hepatic Fibrosis by Schistosoma japonicum Infection
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Author / Creator
Zhou, Wei , Yang, Yingying , Mei, Congjin , Dong, Panpan , Mu, Shasha , Wu, Hongchu , Zhou, Yonghua , Zheng, Yi , Guo, Fukun and Yang, Jun-Qi
Publisher
Switzerland: MDPI AG
Journal title
Language
English
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Publisher
Switzerland: MDPI AG
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Contents
Schistosomiasis is an immunopathogenic disease in which Th17 cells play vital roles. Hepatic granuloma formation and subsequent fibrosis are its main pathologic manifestations and the leading causes of hepatic cirrhosis, and effective therapeutic interventions are lacking. In this study, we explored the effects of fasudil, a selective RhoA-Rho-asso...
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Full title
Inhibition of Rho-Kinase Downregulates Th17 Cells and Ameliorates Hepatic Fibrosis by Schistosoma japonicum Infection
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TN_cdi_doaj_primary_oai_doaj_org_article_60fc06fbc50947d086605913c2fe1ceb
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_60fc06fbc50947d086605913c2fe1ceb
Other Identifiers
ISSN
2073-4409
E-ISSN
2073-4409
DOI
10.3390/cells8101262
