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A non-canonical pathway regulates ER stress signaling and blocks ER stress-induced apoptosis and hea...

A non-canonical pathway regulates ER stress signaling and blocks ER stress-induced apoptosis and hea...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6125403f9aea40e3becc9eae807175b5

A non-canonical pathway regulates ER stress signaling and blocks ER stress-induced apoptosis and heart failure

About this item

Full title

A non-canonical pathway regulates ER stress signaling and blocks ER stress-induced apoptosis and heart failure

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2017-07, Vol.8 (1), p.133-15, Article 133

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Endoplasmic reticulum stress is an evolutionarily conserved cell stress response associated with numerous diseases, including cardiac hypertrophy and heart failure. The major endoplasmic reticulum stress signaling pathway causing cardiac hypertrophy involves endoplasmic reticulum stress sensor PERK (protein kinase-like kinase) and eIF2α-ATF4-CHOP s...

Alternative Titles

Full title

A non-canonical pathway regulates ER stress signaling and blocks ER stress-induced apoptosis and heart failure

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_6125403f9aea40e3becc9eae807175b5

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6125403f9aea40e3becc9eae807175b5

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-017-00171-w

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