Molecular determinants regulating selective binding of autophagy adapters and receptors to ATG8 prot...
Molecular determinants regulating selective binding of autophagy adapters and receptors to ATG8 proteins
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Autophagy is an essential recycling and quality control pathway. Mammalian ATG8 proteins drive autophagosome formation and selective removal of protein aggregates and organelles by recruiting autophagy receptors and adaptors that contain a LC3-interacting region (LIR) motif. LIR motifs can be highly selective for ATG8 subfamily proteins (LC3s/GABAR...
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Full title
Molecular determinants regulating selective binding of autophagy adapters and receptors to ATG8 proteins
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TN_cdi_doaj_primary_oai_doaj_org_article_61625672f9c642f79baf4e0b2c21a97b
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_61625672f9c642f79baf4e0b2c21a97b
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-10059-6
