Targeted degradation of aberrant tau in frontotemporal dementia patient-derived neuronal cell models
Targeted degradation of aberrant tau in frontotemporal dementia patient-derived neuronal cell models
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England: eLife Sciences Publications Ltd
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Language
English
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Publisher
England: eLife Sciences Publications Ltd
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Contents
Tauopathies are neurodegenerative diseases characterized by aberrant forms of tau protein accumulation leading to neuronal death in focal brain areas. Positron emission tomography (PET) tracers that bind to pathological tau are used in diagnosis, but there are no current therapies to eliminate these tau species. We employed targeted protein degrada...
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Full title
Targeted degradation of aberrant tau in frontotemporal dementia patient-derived neuronal cell models
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TN_cdi_doaj_primary_oai_doaj_org_article_61644ae2e0484e5e9ce5e832e02c1ee1
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_61644ae2e0484e5e9ce5e832e02c1ee1
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.45457
