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S-Trimer, a COVID-19 subunit vaccine candidate, induces protective immunity in nonhuman primates

S-Trimer, a COVID-19 subunit vaccine candidate, induces protective immunity in nonhuman primates

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_61db57e69d5a405e82b86f6070a7345d

S-Trimer, a COVID-19 subunit vaccine candidate, induces protective immunity in nonhuman primates

About this item

Full title

S-Trimer, a COVID-19 subunit vaccine candidate, induces protective immunity in nonhuman primates

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2021-03, Vol.12 (1), p.1346-1346, Article 1346

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

SARS-CoV-2 is the underlying cause for the COVID-19 pandemic. Like most enveloped RNA viruses, SARS-CoV-2 uses a homotrimeric surface antigen to gain entry into host cells. Here we describe S-Trimer, a native-like trimeric subunit vaccine candidate for COVID-19 based on Trimer-Tag technology. Immunization of S-Trimer with either AS03 (oil-in-water...

Alternative Titles

Full title

S-Trimer, a COVID-19 subunit vaccine candidate, induces protective immunity in nonhuman primates

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_61db57e69d5a405e82b86f6070a7345d

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_61db57e69d5a405e82b86f6070a7345d

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-021-21634-1

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