S-Trimer, a COVID-19 subunit vaccine candidate, induces protective immunity in nonhuman primates
S-Trimer, a COVID-19 subunit vaccine candidate, induces protective immunity in nonhuman primates
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Author / Creator
Liang, Joshua G. , Su, Danmei , Song, Tian-Zhang , Zeng, Yilan , Huang, Weijin , Wu, Jinhua , Xu, Rong , Luo, Peiwen , Yang, Xiaofang , Zhang, Xiaodong , Luo, Shuangru , Liang, Ying , Li, Xinglin , Huang, Jiaju , Wang, Qiang , Huang, Xueqin , Xu, Qingsong , Luo, Mei , Huang, Anliang , Luo, Dongxia , Zhao, Chenyan , Yang, Fan , Han, Jian-Bao , Zheng, Yong-Tang and Liang, Peng
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
SARS-CoV-2 is the underlying cause for the COVID-19 pandemic. Like most enveloped RNA viruses, SARS-CoV-2 uses a homotrimeric surface antigen to gain entry into host cells. Here we describe S-Trimer, a native-like trimeric subunit vaccine candidate for COVID-19 based on Trimer-Tag technology. Immunization of S-Trimer with either AS03 (oil-in-water...
Alternative Titles
Full title
S-Trimer, a COVID-19 subunit vaccine candidate, induces protective immunity in nonhuman primates
Authors, Artists and Contributors
Author / Creator
Su, Danmei
Song, Tian-Zhang
Zeng, Yilan
Huang, Weijin
Wu, Jinhua
Xu, Rong
Luo, Peiwen
Yang, Xiaofang
Zhang, Xiaodong
Luo, Shuangru
Liang, Ying
Li, Xinglin
Huang, Jiaju
Wang, Qiang
Huang, Xueqin
Xu, Qingsong
Luo, Mei
Huang, Anliang
Luo, Dongxia
Zhao, Chenyan
Yang, Fan
Han, Jian-Bao
Zheng, Yong-Tang
Liang, Peng
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Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_61db57e69d5a405e82b86f6070a7345d
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_61db57e69d5a405e82b86f6070a7345d
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-21634-1