Identification of a BACE1 Binding Peptide Candidate for the Prevention of Amyloid Beta in Alzheimer’...
Identification of a BACE1 Binding Peptide Candidate for the Prevention of Amyloid Beta in Alzheimer’s Disease
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Publisher
Germany: Cell Physiol Biochem Press GmbH & Co KG
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Language
English
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Publisher
Germany: Cell Physiol Biochem Press GmbH & Co KG
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Contents
Amyloid plaques, generated during the progression of Alzheimer's disease, cause major neurological deficits due to substantial cell toxicity and death. The underlying cause of plaque generation stems from cleavage of the amyloid precursor protein (APP) by β-secretase (BACE1). A resulting amyloid-β (Aβ) fragment forms aggregates to produce the main...
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Full title
Identification of a BACE1 Binding Peptide Candidate for the Prevention of Amyloid Beta in Alzheimer’s Disease
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TN_cdi_doaj_primary_oai_doaj_org_article_61fd6258abc94b16868e52103b85f1f2
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_61fd6258abc94b16868e52103b85f1f2
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ISSN
1015-8987
E-ISSN
1421-9778
DOI
10.33594/000000147