Cystine/Glutamate antiporter system xc- deficiency impairs macrophage glutathione metabolism and cyt...
Cystine/Glutamate antiporter system xc- deficiency impairs macrophage glutathione metabolism and cytokine production
About this item
Full title
Author / Creator
Publisher
San Francisco: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
San Francisco: Public Library of Science
Subjects
More information
Scope and Contents
Contents
System x
c
-
, encoded by
Slc7a11
, is an antiporter responsible for exporting glutamate while importing cystine, which is essential for protein synthesis and the formation of thiol peptides, such as glutathione. Glutathione acts as a co-factor for enzymes responsible for scavenging reactive oxygen species. Upon exposure to bacterial...
Alternative Titles
Full title
Cystine/Glutamate antiporter system xc- deficiency impairs macrophage glutathione metabolism and cytokine production
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_624534ec57cb4bd6ad03c03c180b9620
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_624534ec57cb4bd6ad03c03c180b9620
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0291950
