Sialylation converts arthritogenic IgG into inhibitors of collagen-induced arthritis
Sialylation converts arthritogenic IgG into inhibitors of collagen-induced arthritis
About this item
Full title
Author / Creator
Ohmi, Yuhsuke , Ise, Wataru , Harazono, Akira , Takakura, Daisuke , Fukuyama, Hidehiro , Baba, Yoshihiro , Narazaki, Masashi , Shoda, Hirofumi , Takahashi, Nobunori , Ohkawa, Yuki , Ji, Shuting , Sugiyama, Fumihiro , Fujio, Keishi , Kumanogoh, Atsushi , Yamamoto, Kazuhiko , Kawasaki, Nana , Kurosaki, Tomohiro , Takahashi, Yoshimasa and Furukawa, Koichi
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Rheumatoid arthritis (RA)-associated IgG antibodies such as anti-citrullinated protein antibodies (ACPAs) have diverse glycosylation variants; however, key sugar chains modulating the arthritogenic activity of IgG remain to be clarified. Here, we show that reduced sialylation is a common feature of RA-associated IgG in humans and in mouse models of...
Alternative Titles
Full title
Sialylation converts arthritogenic IgG into inhibitors of collagen-induced arthritis
Authors, Artists and Contributors
Author / Creator
Ise, Wataru
Harazono, Akira
Takakura, Daisuke
Fukuyama, Hidehiro
Baba, Yoshihiro
Narazaki, Masashi
Shoda, Hirofumi
Takahashi, Nobunori
Ohkawa, Yuki
Ji, Shuting
Sugiyama, Fumihiro
Fujio, Keishi
Kumanogoh, Atsushi
Yamamoto, Kazuhiko
Kawasaki, Nana
Kurosaki, Tomohiro
Takahashi, Yoshimasa
Furukawa, Koichi
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_626de5323ebb454892d4e77327d0fdec
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_626de5323ebb454892d4e77327d0fdec
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms11205
