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CircFOXO3 protects against osteoarthritis by targeting its parental gene FOXO3 and activating PI3K/A...

CircFOXO3 protects against osteoarthritis by targeting its parental gene FOXO3 and activating PI3K/A...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_626f9681e1ab4993a69e82a25f00ebca

CircFOXO3 protects against osteoarthritis by targeting its parental gene FOXO3 and activating PI3K/AKT-mediated autophagy

About this item

Full title

CircFOXO3 protects against osteoarthritis by targeting its parental gene FOXO3 and activating PI3K/AKT-mediated autophagy

Publisher

London: Nature Publishing Group UK

Journal title

Cell death & disease, 2022-11, Vol.13 (11), p.932-932, Article 932

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Osteoarthritis (OA) is a degenerative joint disorder causing pain and functional disability. Emerging evidence reveals that circular RNAs (circRNAs) play essential roles in OA progression and development. This study aimed to investigate the role of a novel circRNA factor, circFOXO3, in the progression of OA and elucidate its underlying molecular me...

Alternative Titles

Full title

CircFOXO3 protects against osteoarthritis by targeting its parental gene FOXO3 and activating PI3K/AKT-mediated autophagy

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_626f9681e1ab4993a69e82a25f00ebca

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_626f9681e1ab4993a69e82a25f00ebca

Other Identifiers

ISSN

2041-4889

E-ISSN

2041-4889

DOI

10.1038/s41419-022-05390-8

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