Systematic assessment of tissue dissociation and storage biases in single-cell and single-nucleus RN...
Systematic assessment of tissue dissociation and storage biases in single-cell and single-nucleus RNA-seq workflows
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Publisher
England: BioMed Central Ltd
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Language
English
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England: BioMed Central Ltd
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Contents
Single-cell RNA sequencing has been widely adopted to estimate the cellular composition of heterogeneous tissues and obtain transcriptional profiles of individual cells. Multiple approaches for optimal sample dissociation and storage of single cells have been proposed as have single-nuclei profiling methods. What has been lacking is a systematic co...
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Full title
Systematic assessment of tissue dissociation and storage biases in single-cell and single-nucleus RNA-seq workflows
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TN_cdi_doaj_primary_oai_doaj_org_article_6277e593d81c45568b782002f7c58599
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6277e593d81c45568b782002f7c58599
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ISSN
1474-760X,1474-7596
E-ISSN
1474-760X
DOI
10.1186/s13059-020-02048-6