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Linking post-translational modifications and protein turnover by site-resolved protein turnover prof...

Linking post-translational modifications and protein turnover by site-resolved protein turnover prof...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_629f5a02a56949d3a37bcf1ab0caac97

Linking post-translational modifications and protein turnover by site-resolved protein turnover profiling

About this item

Full title

Linking post-translational modifications and protein turnover by site-resolved protein turnover profiling

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2022-01, Vol.13 (1), p.165-14, Article 165

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Proteome-wide measurements of protein turnover have largely ignored the impact of post-translational modifications (PTMs). To address this gap, we employ stable isotope labeling and mass spectrometry to measure the turnover of >120,000 peptidoforms including >33,000 phosphorylated, acetylated, and ubiquitinated peptides for >9,000 native proteins....

Alternative Titles

Full title

Linking post-translational modifications and protein turnover by site-resolved protein turnover profiling

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_629f5a02a56949d3a37bcf1ab0caac97

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_629f5a02a56949d3a37bcf1ab0caac97

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-021-27639-0

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