Linking post-translational modifications and protein turnover by site-resolved protein turnover prof...
Linking post-translational modifications and protein turnover by site-resolved protein turnover profiling
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Proteome-wide measurements of protein turnover have largely ignored the impact of post-translational modifications (PTMs). To address this gap, we employ stable isotope labeling and mass spectrometry to measure the turnover of >120,000 peptidoforms including >33,000 phosphorylated, acetylated, and ubiquitinated peptides for >9,000 native proteins....
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Linking post-translational modifications and protein turnover by site-resolved protein turnover profiling
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TN_cdi_doaj_primary_oai_doaj_org_article_629f5a02a56949d3a37bcf1ab0caac97
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_629f5a02a56949d3a37bcf1ab0caac97
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-27639-0