Glutamine exerts a protective effect on osteoarthritis development by inhibiting the Jun N-terminal...
Glutamine exerts a protective effect on osteoarthritis development by inhibiting the Jun N-terminal kinase and nuclear factor kappa-B signaling pathways
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Author / Creator
Zhong, Lin , Cao, Le , Song, Rui , Yang, Xue-Fei , Li, Jia-Le , Yang, Hai-Tao , Zhou, Hong-Xiang and Fan, Hai-Tao
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Strategies for treating osteoarthritis (OA) have become a research focus because an effective treatment for OA is unavailable. The objective of this study was to explore the effects and underlying mechanisms of glutamine (Gln) in OA. First, the chondrocytes were identified and a standard IL-1β-induced OA model was established. After treatment with...
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Full title
Glutamine exerts a protective effect on osteoarthritis development by inhibiting the Jun N-terminal kinase and nuclear factor kappa-B signaling pathways
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_62e83f4be2004a6caf541a0231963b72
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_62e83f4be2004a6caf541a0231963b72
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-022-16093-7
