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NUP98‐BPTF promotes oncogenic transformation through PIM1 upregulation

NUP98‐BPTF promotes oncogenic transformation through PIM1 upregulation

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_62eef3402d8c4ee5810cff35ce56134f

NUP98‐BPTF promotes oncogenic transformation through PIM1 upregulation

About this item

Full title

NUP98‐BPTF promotes oncogenic transformation through PIM1 upregulation

Publisher

United States: John Wiley & Sons, Inc

Journal title

Cancer medicine (Malden, MA), 2024-07, Vol.13 (13), p.e7445-n/a

Language

English

Formats

Publication information

Publisher

United States: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

Introduction
Nucleoporin 98 (NUP98) fusion proteins are recurrently found in leukemia and are associated with unfavorable clinical outcomes. They are distributed to the nucleus and contribute to leukemogenesis via aberrant transcriptional regulation. We previously identified NUP98‐BPTF (NB) fusion in patients with T‐cell acute lymphoblastic leuk...

Alternative Titles

Full title

NUP98‐BPTF promotes oncogenic transformation through PIM1 upregulation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_62eef3402d8c4ee5810cff35ce56134f

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_62eef3402d8c4ee5810cff35ce56134f

Other Identifiers

ISSN

2045-7634

E-ISSN

2045-7634

DOI

10.1002/cam4.7445

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