Determining doses for backfill cohorts based on patient-reported outcome
Determining doses for backfill cohorts based on patient-reported outcome
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Publisher
England: BioMed Central Ltd
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English
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Publisher
England: BioMed Central Ltd
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Contents
Incorporating backfill cohorts in phase I oncology trials is a recently developed strategy for dose optimization. However, the efficacy assessment window is long in general, causing a lag in identifying ineffective doses and more patients being backfilled to those doses. There is necessity to investigate how to use patient-reported outcomes (PRO) t...
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Full title
Determining doses for backfill cohorts based on patient-reported outcome
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TN_cdi_doaj_primary_oai_doaj_org_article_62f600a0f0104a43b2cc305a31edbf70
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_62f600a0f0104a43b2cc305a31edbf70
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ISSN
1471-2288
E-ISSN
1471-2288
DOI
10.1186/s12874-024-02398-w