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Determining doses for backfill cohorts based on patient-reported outcome

Determining doses for backfill cohorts based on patient-reported outcome

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_62f600a0f0104a43b2cc305a31edbf70

Determining doses for backfill cohorts based on patient-reported outcome

About this item

Full title

Determining doses for backfill cohorts based on patient-reported outcome

Publisher

England: BioMed Central Ltd

Journal title

BMC medical research methodology, 2024-11, Vol.24 (1), p.270-12, Article 270

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Incorporating backfill cohorts in phase I oncology trials is a recently developed strategy for dose optimization. However, the efficacy assessment window is long in general, causing a lag in identifying ineffective doses and more patients being backfilled to those doses. There is necessity to investigate how to use patient-reported outcomes (PRO) t...

Alternative Titles

Full title

Determining doses for backfill cohorts based on patient-reported outcome

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_62f600a0f0104a43b2cc305a31edbf70

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_62f600a0f0104a43b2cc305a31edbf70

Other Identifiers

ISSN

1471-2288

E-ISSN

1471-2288

DOI

10.1186/s12874-024-02398-w

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