Low-dose intranasal deferoxamine modulates memory, neuroinflammation, and the neuronal transcriptome...
Low-dose intranasal deferoxamine modulates memory, neuroinflammation, and the neuronal transcriptome in the streptozotocin rodent model of Alzheimer's disease
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Switzerland: Frontiers Research Foundation
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English
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Switzerland: Frontiers Research Foundation
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Intranasal (IN) deferoxamine (DFO) has emerged over the past decade as a promising therapeutic in preclinical experiments across neurodegenerative and neurovascular diseases. As an antioxidant iron chelator, its mechanisms are multimodal, involving the binding of brain iron and the consequent engagement of several pathways to counter pathogenesis a...
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Low-dose intranasal deferoxamine modulates memory, neuroinflammation, and the neuronal transcriptome in the streptozotocin rodent model of Alzheimer's disease
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TN_cdi_doaj_primary_oai_doaj_org_article_62fdcf6067284589b983a007a9d72c0b
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_62fdcf6067284589b983a007a9d72c0b
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1662-4548,1662-453X
E-ISSN
1662-453X
DOI
10.3389/fnins.2024.1528374
