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KMT2A‐D pathogenicity, prevalence, and variation according to a population database

KMT2A‐D pathogenicity, prevalence, and variation according to a population database

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6318ddd9326e4291b5eee4aaa9172e1e

KMT2A‐D pathogenicity, prevalence, and variation according to a population database

About this item

Full title

KMT2A‐D pathogenicity, prevalence, and variation according to a population database

Publisher

United States: John Wiley & Sons, Inc

Journal title

Cancer medicine (Malden, MA), 2023-03, Vol.12 (6), p.7234-7245

Language

English

Formats

Publication information

Publisher

United States: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

Introduction
The KMT2 family of genes is essential epigenetic regulators promoting gene expression. The gene family contains three subgroups, each with two paralogues: KMT2A and KMT2B; KMT2C and KMT2D; KMT2F and KMT2G. KMT2A‐D are among the most frequent somatically altered genes in several different cancer types. Somatic KMT2A rearrangements ar...

Alternative Titles

Full title

KMT2A‐D pathogenicity, prevalence, and variation according to a population database

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_6318ddd9326e4291b5eee4aaa9172e1e

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_6318ddd9326e4291b5eee4aaa9172e1e

Other Identifiers

ISSN

2045-7634

E-ISSN

2045-7634

DOI

10.1002/cam4.5443

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